<p> Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells. </p> <p> This entry represents Interleukin-22 (IL-22), that belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26 [<cite idref="PUB00046044"/>]. It is produced by activated T cells and acts as a T cell mediator, promoting the innate, non-specific immunity of tissues [<cite idref="PUB00046082"/>]. IL-22 also regulates early defence mechanisms against attaching and effacing (A/E) bacterial pathogens [<cite idref="PUB00046083"/>]. </p> Interleukin-22